Safekipedia
ChemistryMatterMolecular physicsMolecules

Molecule

Adapted from Wikipedia · Adventurer experience

The Crab Nebula is a beautiful cloud of glowing gas formed from the explosion of a star, showing incredible colors from different elements in space.

A molecule is a group of two or more atoms held together by attractive forces called chemical bonds. These tiny parts make up everything around us, like the air we breathe and the water we drink. Molecules can be made of atoms of the same element, like the oxygen molecule (O2), or they can mix atoms of different elements, such as in water (H2O), which has two hydrogen atoms and one oxygen atom.

Atomic force microscopy (AFM) image of a PTCDA molecule, in which the five six-carbon rings are visible

People have studied molecules for hundreds of years. Scientists like Robert Boyle, Amedeo Avogadro, Jean Perrin, and Linus Pauling helped learn more about them. Today, knowing about molecules is important in areas like quantum physics, organic chemistry, and biochemistry. Molecules help us understand how living things grow and what makes everyday materials special.

Etymology

The word "molecule" comes from an old Latin word, "moles", meaning a small piece of matter. It then passed through French, becoming molécule. Scientists like René Descartes helped make this word well-known. This term let people discuss tiny parts of matter in a new way.

History

Main article: History of molecular theory

Marc Antoine Auguste Gaudin's volume diagrams of molecules in the gas phase (1833)

The idea of what a molecule is has changed as we learned more about atoms. Long ago, thinkers like Leucippus and Democritus believed everything was made of tiny pieces called atoms. Later, Robert Boyle suggested that matter is made of clusters of particles.

The word "molecule" was first used by Amedeo Avogadro. He suggested that the smallest pieces of gases are groups of atoms stuck together. In the 1920s, scientists used new ideas to explain how atoms bond together to form molecules. This helped us learn about the shapes and properties of different molecules.

Molecular science

The study of molecules is called molecular chemistry or molecular physics, depending on whether we are looking at chemistry or physics. Molecular chemistry looks at how molecules work together and form new bonds. Molecular physics studies the shape and features of molecules. In simple words, a molecule is a group of two or more atoms stuck together. Sometimes, charged groups of atoms called polyatomic ions are also thought of as molecules. The term "unstable molecule" means groups of atoms that change quickly, such as radicals or molecular ions.

Prevalence

Molecules are everywhere! They are in the air we breathe and the water in our oceans. Important things in our bodies, like proteins and DNA, are molecules too.

But not everything is made of molecules. Many solid things, like rocks, sand, and metals, are not made of molecules. Instead, they are made of tiny building blocks that repeat in patterns. For example, diamond and quartz are made of repeating patterns, not separate molecules.

Bonding

Molecules are held together by covalent bonding. In this type of bonding, atoms share pairs of electrons to stay connected. Many non-metal elements, like hydrogen, exist as molecules instead of single atoms.

Atoms can also bond through ionic bonding. This happens when one atom gives up electrons to another. This creates charged particles called cations and anions. These charges pull toward each other and form a bond. This type of bonding usually makes solid materials. Sometimes it can make separate molecules when heated or turned into gas.

Molecular size

Most molecules are too small to see without special tools, but some very large molecules, like DNA, can be big enough to see. Small building block molecules are measured in angstroms, which are very tiny units—about one billionth of a meter. We usually can't see single molecules with regular light, but special tools like an atomic force microscope can sometimes show us their shapes.

The smallest molecule is hydrogen, made of two atoms stuck together. It is very tiny, with a distance between its atoms of just 0.74 angstroms. Molecules can change size when they are dissolved in water or other liquids.

Molecular formulas

Main article: Chemical formula

3D (left and center) and 2D (right) representations of the terpenoid molecule atisane

A chemical formula shows what a molecule is made of using letters and numbers. The letters are symbols for elements, like H for hydrogen or O for oxygen. Numbers can tell us how many atoms of each element are in the molecule. For example, the formula for water is H2O, meaning each water molecule has two hydrogen atoms and one oxygen atom.

There are different kinds of formulas. One is called the empirical formula, which shows the simplest whole-number ratio of atoms in a molecule. Another is the molecular formula, which tells exactly how many atoms of each element are in a single molecule. Sometimes, different molecules can have the same molecular formula but arranged in different ways—these are called isomers.

Molecular geometry

Structure and STM image of a "cyanostar" dendrimer molecule

Main article: Molecular geometry

Molecules have special shapes. The distance between atoms and the angles between bonds are fixed. These shapes, along with a molecule's chemical formula, help decide what the molecule can do and how it acts. Molecules with the same formula but different shapes, called isomers, can have very different properties because of how their atoms are arranged.

Molecular spectroscopy

Main article: Spectroscopy

Hydrogen can be removed from individual H2TPP molecules by applying excess voltage to the tip of a scanning tunneling microscope (STM, a); this removal alters the current–voltage (I–V) curves of TPP molecules, measured using the same STM tip, from diode like (red curve in b) to resistor like (green curve). Image (c) shows a row of TPP, H2TPP and TPP molecules. While scanning image (d), excess voltage was applied to H2TPP at the black dot, which instantly removed hydrogen, as shown in the bottom part of (d) and in the rescan image (e). Such manipulations can be used in single-molecule electronics.

Molecular spectroscopy is the study of how molecules react to energy. When we send signals of certain energy or frequency toward molecules, we can learn about them by seeing how they absorb or give off energy. This helps scientists find and learn about molecules.

Different types of spectroscopy look at different actions of molecules. For example, microwave spectroscopy measures how molecules spin, which helps find molecules in space. Infrared spectroscopy looks at how molecules move back and forth, which can tell us what kinds of bonds are present. Other types of spectroscopy study how the tiny parts inside molecules behave, helping us understand how atoms are arranged.

Theoretical aspects

The study of molecules uses ideas from quantum mechanics to help us understand how atoms join together to form chemical bonds. The simplest molecule is the hydrogen molecule-ion, H2+, made of two protons and one electron. Because it has only one electron, scientists can study its behavior more easily.

Scientists say a molecule is a group of atoms that stick together strongly enough to act like one unit. This can include very weakly bound groups, like the helium dimer, He2, which only stays together at very low temperatures. A molecule isn’t a basic piece of nature like an elementary particle; it’s a helpful idea that chemists use to talk about how atoms interact.

Main article: theoretical chemistry

Images

A close-up image of a special molecule called TOAT, showing its structure on a copper surface.
A beautiful butterfly called Issoria lathonia resting on colorful flowers.
A 3D model showing the structure of nitrous oxide, a chemical compound made of nitrogen and oxygen atoms.
A 3D model showing the structure of ethanol, a type of chemical commonly studied in science classes.
A 3D model showing the structure of a Buckminsterfullerene molecule, made up of carbon atoms connected in a pattern resembling a soccer ball.
A scientific image showing the structure of pentacene molecules on a metal surface, viewed using a special microscope.
Animation showing how sodium and fluorine atoms form an ionic bond to create sodium fluoride.

This article is a child-friendly adaptation of the Wikipedia article on Molecule, available under CC BY-SA 4.0.

Images from Wikimedia Commons. Tap any image to view credits and license.