| County | Location | mi | km | Destinations |
|---|
| Culberson | Van Horn | 0.0 | 0.0 |  
 I-10 BL to SH 54 – Guadalupe Mountains National Park, Carlsbad Caverns National Park |
|---|
| 0.2 | 0.32 | I-10 – San Antonio, El Paso |
|---|
| | 12.0 | 19.3 | 
FM 1523 south |
|---|
| Lobo | 17.8 | 28.6 | 
FM 1523 north |
|---|
| Jeff Davis | | 21.6 | 34.8 | 
FM 2017 north |
|---|
| | 45.5 | 73.2 | RM 505 – Fort Davis National Historic Site, Davis Mountains State Park, McDonald Observatory & Visitor Center |
|---|
| Presidio | Marfa | 73.0 | 117.5 | 
RM 2810 south (Hoover Street) |
|---|
| 73.6 | 118.4 | 
 
US 67 south / SH 17 north – Fort Davis, Fort Davis National Historic Site, McDonald Observatory and Visitor Center, Presidio |
|---|
| Brewster | | 98.3 | 158.2 | 
FM 1703 north |
|---|
| Alpine | 99.7 | 160.5 | 
SH 118 north (5th Street) – Fort Davis, Fort Davis National Historic Site, McDonald Observatory and Visitor Center |
|---|
| 100.1 | 161.1 | 
SH 118 south (Cockrell Street) – Big Bend National Park Headquarters |
|---|
| 100.2 | 161.3 | 
SH 223 north (North Harrison Street) |
|---|
| Altuda | 107.9 | 173.6 | 
US 67 north – Fort Stockton |
|---|
| Marathon | 130.5 | 210.0 | 
US 385 south – Big Bend National Park Headquarters |
|---|
| | 131.6 | 211.8 | 
US 385 north – Fort Stockton |
|---|
Pecos
| No major junctions |
| Terrell | Sanderson | | | 
US 285 north – Fort Stockton |
|---|
| Dryden | | | 
SH 349 north – Sheffield, Iraan |
|---|
| | | | 
RM 1865 north – Pumpville |
|---|
| Val Verde | | | | 
Loop 25 east – Langtry, Judge Roy Bean Museum |
|---|
| | | | 
Loop 25 west – Langtry, Judge Roy Bean Museum |
|---|
| | | | Pecos River Bridge over Pecos River |
|---|
| | | | PR 67 – Seminole Canyon State Historical Park |
|---|
| Comstock | | | 
RM 1024 north – Pandale |
|---|
| | 
SH 163 north – Ozona, Barnhart |
|---|
| | | | Spur 406 – Amistad National Recreation Area |
|---|
| | | | Spur 349 – Port of Entry, Amistad Dam, Amistad Reservoir, Amistad National Recreation Area, Governors Landing |
|---|
| | | | Spur 454 – Amistad National Recreation Area |
|---|
| Del Rio | | | 
Loop 79 south – Sonora, Junction, Uvalde |
|---|
| | 
 
US 277 north / US 377 north – Rocksprings, Junction, Sonora |
|---|
| | 
 
Spur 239 south (East Gibbs Street) / Spur 297 south (Veteran's Boulevard) – Ciudad Acuña, Business District |
|---|
| | 
US 277 south (Bedell Avenue) – Eagle Pass, Laredo |
|---|
| | RM 2523 – Carta Valley |
|---|
| | Loop 79 – Sonora, Junction, Eagle Pass |
|---|
| Kinney | | | | 
 
RM 3008 north to RM 2523 – Rocksprings |
|---|
| | | | 
 
RM 693 south to US 277 – Quemado |
|---|
| Brackettville | | | RM 2804 |
|---|
| | 
Loop 166 east |
|---|
| | 
RM 3348 south (Las Moras Road) – Fort Clark Springs |
|---|
| |  RM 334 / RM 674 – Rocksprings, Kickapoo Cavern State Park |
|---|
| | 
SH 131 south – Spofford, Eagle Pass |
|---|
| | 
Loop 166 west |
|---|
| | | | 
FM 1572 west – Spofford |
|---|
| Uvalde | | | | 
RM 1022 south – Blewett |
|---|
| | | | Nueces River Bridge over Nueces River |
|---|
| | | | 
 
FM 2369 east (Dunbar Lane) to FM 1403 – Rocksprings |
|---|
| Uvalde | | | 
FM 481 south – Eagle Pass |
|---|
| | 
FM 1052 north |
|---|
| | 
FM 1435 south (Evans Street) |
|---|
| | 
FM 1435 north (Grove Street) |
|---|
| |  
US 83 / SH 55 north (Getty Street) – Leakey, Junction, Rocksprings, Crystal City, Laredo |
|---|
| | 
FM 1023 north (4th Street) |
|---|
| | 
 
 FM 1023 south (Garner Field Road) to FM 1049 – Uvalde Garner Field Airport |
|---|
| | 
FM 3447 north |
|---|
| | 
 
 FM 1574 south to FM 1023 – Airport |
|---|
| | | | 
FM 2369 west – Uvalde |
|---|
| Knippa | | | 
FM 1049 north – Concan |
|---|
| | 
 
FM 1049 south to FM 1023 |
|---|
| | | | 
 
FM 2730 north to SH 127 |
|---|
| Sabinal | | | 
 SH 127 north / RM 187 – Utopia, Leakey, Concan, Garner State Park, Pearsall |
|---|
| Medina | D'Hanis | | | 
FM 1796 north |
|---|
| | 
FM 2200 south – Yancey |
|---|
| Hondo | | | 
 
FM 1250 east to FM 462 |
|---|
| | 
FM 462 north / Avenue M – Tarpley |
|---|
| | 
 FM 462 south / Avenue E – Yancey |
|---|
| | | | SH 173 – Bandera, Devine |
|---|
| Castroville | | | 
 
FM 1343 south to County Road 4516 / SH 173 – Quihi |
|---|
| | 
FM 471 north – Rio Medina |
|---|
| | 
 FM 471 south – Castroville Airport, La Coste, Natalia |
|---|
| Bexar | | | | SH 211 |
|---|
| | | | Montgomery Road |
|---|
| San Antonio | | | Loop 1604 (Anderson Loop) |
|---|
| | Hunt Lane / Ray Ellison Drive |
|---|
| |   I-410 / SH 16 – Airport |
|---|
| | Loop 13 (Military Drive) – Lackland AFB |
|---|
| | Old Highway 90 |
|---|
| | Callaghan Road |
|---|
| | Acme Road |
|---|
| | SH 151 (Stotzer Freeway) – SeaWorld |
|---|
| | 36th Street – Port San Antonio |
|---|
| | General McMullen Drive |
|---|
| | Cupples Road |
|---|
| | Spur 371 (General Hudnell Drive) – Port San Antonio |
|---|
| | Zarzamora Street |
|---|
| | 
Loop 353 south (Nogalitos Street) |
|---|
| | 
  
I-10 west / I-35 / US 87 north – El Paso, Austin, Laredo |
|---|
| see I-10 |
| Guadalupe | Seguin | | | 
I-10 east – Houston |
|---|
| | | |  
FM 725 to I-10 – McQueeney, Stockdale |
|---|
| Seguin | | | 

 
 
US 90 Alt. east / FM 464 west to I-10 – McQueeney, Gonzales |
|---|
| |  

 
SH 46 (Sam Flores Drive) to US 90 Alt. / I-10 – New Braunfels, Gonzales |
|---|
| | 
 
FM 78 west (Eighth Street) to I-10 – Marion, Schertz |
|---|
| | 
 
Bus. SH 123 (North Austin Street) to I-10 – San Marcos, Stockdale |
|---|
| | 
FM 466 east (North King Street) – Cost |
|---|
| |  
SH 123 to I-10 – San Marcos, Stockdale |
|---|
| | I-10 – San Antonio, Houston |
|---|
| | 
SH 130 Toll north – Austin |
|---|
| Kingsbury | | | 
 

 
FM 2438 south to US 90 Alt. / I-10 |
|---|
| | 
 
FM 1104 east to I-10 |
|---|
| Caldwell | Luling | | | 
  
US 183 north / SH 80 to I-10 – Lockhart, San Marcos, Nixon |
|---|
| | 
 
US 183 south to I-10 – Gonzales |
|---|
| Gonzales | Harwood | | | 
 
FM 794 south to I-10 – Gonzales |
|---|
| | | |  
SH 304 to I-10 – Bastrop, Gonzales |
|---|
| Waelder | | | 
 
 
 
SH 97 west / FM 1115 north to I-10 / FM 1296 – Smithville, Gonzales |
|---|
| | 
FM 1680 south – Moulton |
|---|
| | | | I-10 – Houston, San Antonio |
|---|
| Fayette | Flatonia | | | 
 
FM 2762 west to FM 1115 – Cistern |
|---|
| | 
SH 95 south – Moulton, Shiner |
|---|
| | 
 
SH 95 north to I-10 – Smithville, Bastrop, Komensky |
|---|
| | 
 
FM 609 north to I-10 – La Grange |
|---|
| | | | 
FM 1295 south – Praha, Komensky |
|---|
| Engle | | | 
 
FM 2238 north to I-10 – Freyburg |
|---|
| Schulenburg | | | 
FM 2672 north – High Hill |
|---|
| | 
FM 957 south – Hallettsville |
|---|
| |  
Loop 222 (Lyons Avenue) to US 77 – Hallettsville |
|---|
| |  
US 77 to I-10 – La Grange, Hallettsville |
|---|
| | | | 
FM 1579 east |
|---|
| | | | I-10 – San Antonio, Houston |
|---|
| | | | 
FM 1383 north – Dubina, Ammannsville |
|---|
| Colorado | Weimar | | | 
FM 155 north – La Grange |
|---|
| | 
 
FM 155 south to I-10 – Sublime |
|---|
| | | | I-10 / Hattermann Lane – Houston, San Antonio |
|---|
| Glidden | | | 
 
FM 2434 west to I-10 – Oakland |
|---|
| | | |  
SH 71 to I-10 – La Grange, Austin, El Campo |
|---|
| Columbus | | | 
FM 806 south (Cardinal Lane) – Rock Island |
|---|
| | 
 
Bus. SH 71 (Fannin Street) to I-10 – La Grange, El Campo |
|---|
| | Spur 52 (Milam Street) |
|---|
| | Colorado River Bridge over Colorado River |
|---|
| | | | 
I-10 west – San Antonio |
|---|
| see I-10 |
| Austin | Sealy | | | 
 
I-10 east / FM 3538 south – Houston |
|---|
| |  
 
 
Loop 350 to SH 36 / I-10 / SH 60 – Bellville, Wallis, Wharton, Rosenberg |
|---|
| | 
I-10 west / Outlet Center Drive – San Antonio |
|---|
| see I-10 |
| Waller | | | | 
I-10 east / Peach Ridge Road / Donigan Road – Houston |
|---|
| Brookshire | | | 
 
FM 1489 south to I-10 – Simonton, Orchard |
|---|
| | 
 
FM 359 north / FM 362 north – Pattison, Hempstead, Waller |
|---|
| | 
 
FM 359 south to I-10 – Fulshear, Pecan Grove |
|---|
| | | | 
FM 2855 north |
|---|
| Fort Bend | Katy | | | 
 
FM 1463 south to FM 359 – Richmond, Pecan Grove |
|---|
| Harris | | | 
I-10 west / Katy Mills Boulevard – San Antonio |
|---|
| see I-10 |
| Harris | Houston | | | 
I-10 east – Beaumont |
|---|
| | I-610 – Pasadena, Galveston, Lufkin |
|---|
| | Mercury Drive |
|---|
| | 
 
FM 526 south (Maxey Road) to Wallisville Road / I-10 – Galena Park |
|---|
| | 
 
FM 526 north (Normandy Street) to I-10 – Galena Park |
|---|
| | | |   
Beltway 8 / Sam Houston Tollway to I-10 – Humble, Pasadena / Uvalde Road |
|---|
| | | | Miller Road No. 3 |
|---|
| | | | Miller Road No. 2 |
|---|
| Sheldon | | | Sheldon Road |
|---|
| | Frontage Road |
|---|
| Barrett–Crosby line | | | County Road |
|---|
| |  FM 1942 / FM 2100 (US 90 Bus. west) – Huffman, Mont Belvieu |
|---|
| | Krenek Road / Runneburg Road |
|---|
| Liberty | | | | SH 99 Toll (Grand Parkway) – Spring, Baytown |
|---|
| | | | 
FM 1413 south |
|---|
| Dayton | | | 
 
SH 146 south to I-10 – Mont Belvieu, Baytown |
|---|
| | 
 
 
SH 321 north to FM 1008 / FM 1960 – Cleveland, Kenefick, Humble |
|---|
| | 
FM 1409 south – Old River-Winfree |
|---|
| Liberty | | | 
 
 
Loop 227 north / FM 2684 south to SH 146 – Rye, Livingston |
|---|
| | 
 
FM 563 south to I-10 – Anahuac, Wallisville |
|---|
| | 
SH 146 north – Hardin, Rye, Livingston |
|---|
| Ames | | | FM 160 (MLK Road) |
|---|
| | 
 
FM 1909 north to FM 160 |
|---|
| | | | 
 
FM 2830 north to FM 160 |
|---|
| Raywood | | | 
 
 
FM 770 south to FM 563 / I-10 – Anahuac, Wallisville |
|---|
| | 
FM 770 north – Daisetta, Saratoga, Kountze |
|---|
| Devers | | | 
 
 
SH 61 south to I-10 / FM 1410 – Anahuac, Hankamer, Winnie |
|---|
| | | | 
FM 1009 east – Nome |
|---|
| Jefferson | Nome | | | 
FM 1009 west – Liberty |
|---|
| | 
 
 
 
SH 326 north / FM 365 east to FM 1406 / I-10 – Sour Lake, Fannett, Winnie |
|---|
| Beaumont | | |  
 
FM 364 (Major Drive) to I-10 / SH 105 |
|---|
| |    I-10 / US 69 / US 96 / US 287 – Lake Charles, Lufkin, Jasper, Houston, Port Arthur |
|---|
| see I-10 |
| Orange | Orange | | | 
 
I-10 east / US 90 east – Lake Charles, Lafayette |
|---|
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
|