Region Location Map Principal communities Population Central Oregon Deschutes , Crook , Jefferson countiesBend , Redmond , Madras , Prineville 219,564 Eastern Oregon Baker , Grant , Harney , Malheur , Morrow , Umatilla , Union , Wallowa countiesHermiston , Pendleton , La Grande , Ontario , Baker City 181,137 Northwest Oregon Clatsop , Columbia , and Tillamook countiesAstoria , St. Helens , Scappoose , Tillamook 113,084 Southeastern Oregon /Oregon Outback Harney , Klamath , Lake , and Malheur countiesKlamath Falls , Lakeview , Burns , Ontario 111,425 Southern Oregon Douglas , Jackson , Josephine , and Klamath countiesMedford , Grants Pass , Roseburg , Klamath Falls 471,013 Western Oregon West of the Cascades, Lane County and north Portland , Salem , Eugene 3,010,021 Applegate Valley Southwestern Jackson and eastern Josephine counties along the Applegate River Applegate , Ruch Not available Cascade Range Cascade Mountains N/A Not available Catlow Valley Southwestern Harney County Blitzen (formerly)Not available Columbia Plateau Northeastern area around the Columbia River Hermiston , Hood River , Pendleton , The Dalles , Milton-Freewater Not available Columbia River Gorge Parts of Multnomah , Hood River , and Wasco counties Hood River , The Dalles Not available Eagle Valley Eastern Baker County Richland , New Bridge , Sparta Not available French Prairie Northern Marion County Woodburn , Aurora , Butteville , Donald , Gervais , Hubbard , Saint Louis , St. Paul Not available Goose Lake Valley Southern Lake County Lakeview 7,829 Harney Basin Northern and central Harney County Burns , Hines 7,200 High Desert Southeastern Oregon Bend , Burns , Lakeview , Prineville , Redmond Not available Hood River Valley Hood River County Hood River 23,137 Klamath Basin Southern Klamath County Klamath Falls , Altamont 66,016 Mount Hood Corridor Clackamas County along U.S. 26 Government Camp , Mount Hood Village , Sandy Not available Oregon Coast Areas bordering the Pacific Ocean Astoria , Tillamook , Lincoln City , Newport , Florence , Coos Bay , Brookings Not available Portland metropolitan area Area around Portland Portland , Gresham , Hillsboro , Beaverton 1,918,394 Rogue Valley Along the Rogue River in Jackson and Josephine counties Medford , Ashland , Grants Pass 297,312 Treasure Valley Along the Snake River in northeastern Malheur County Ontario , Nyssa , Vale Not available Trout Creek Mountains Southern Malheur and Harney counties McDermitt Not available Tualatin Valley Along the Tualatin River in Washington and Clackamas counties Tigard , Tualatin , Sherwood , Beaverton , Aloha , Hillsboro , Forest Grove , West Linn Not available Umpqua Valley Douglas County Roseburg Not available Wallowa Valley Wallowa County along the Wallowa River Enterprise , Joseph , Lostine , Wallowa 6,856 Warner Valley Southeastern Lake County around the Warner Lakes Adel , Plush Not available Willamette Valley Area along the Willamette River Portland , Salem , Albany , Corvallis , Eugene Not available 
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